UT Anti-infective agents PDF / PPT
Medicinal Chemistry-III Urinary Tract Anti-infective Agentswww.DuloMix.com 1 Quinolones• Synthetic substances possessing in common an N-1-alkylated 3-carboxypyrid-4-onering fused…
Sulphonamides PDF / PPT
Medicinal Chemistry-III Sulphonamides www.DuloMix.com 1 Historical Development• First effective chemotherapeutic agents that could be used systemically for…
Quantitative Structure Activity Relationship (QSAR)
Medicinal Chemistry-III Quantitative Structure ActivityRelationship (QSAR) www.DuloMix.com 1 Quantitative Structure Activity Relationship• Change in physico-chemical properties…
Prodrugs PDF / PPT
Prodrugs www.DuloMix.com 1 Prodrugs • Initially used by Albert• Is a pharmacologically inactive compound that is convertedinto an…
Cardiovascular Agents PDF / PPT
CARDIOVASCULAR AGENTS Contents ➢ Description of Cardiovascular agents ➢ Anti-angina agents – Coronary artery diseases ➢ Intermediary myocardial…
Docking & Pharmacophore modelling PDF / PPT
Medicinal Chemistry-III Molecular Docking &Pharmacophore Modelling 1 Pharmacophore modelling• Common features in a molecule: • Hydrogen bond donors…
Diuretics PDF / PPT
Diuretic Drugs www.DuloMix.comDiuretics (“water pills”) are the drugs whichincrease the urine out put (or) urine volume . …
Combinatorial Chemistry PDF / PPT
Medicinal Chemistry-III Combinatorial Chemistry www.DuloMix.com Combinatorial Chemistry• Combinatorial and parallel synthesis have become established tools in drug discoveryand…
β lactam Antibiotics penicillins and β lactamase inhibitors
Antibiotics 3β-lactam Antibiotics-penicillinsandβ-lactamase inhibitors Contents • Chemical degradation of penicillins – various pathways • Study of individual penicillins…
Hybridization PDF / PPT
Lecture No. 03 Hybridisation Contents • Hybridisation • SP2 • Sp3 • Sp • Bong angles •…