Pharmaceutical product development sem 8 (polyethylene glycol sorbitol) hand written notes pdf

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Polyethylene glycol sorbitol is a mixture of two compounds: polyethylene glycol and sorbitol. It is commonly used as a laxative, where it acts by drawing water into the colon to soften the stools and facilitate bowel movements.

Polyethylene glycol is a water-soluble polymer that is widely used in various industries, including pharmaceuticals, cosmetics, and food. It is chemically inert and has a high molecular weight, which makes it highly effective as a laxative.

Sorbitol, on the other hand, is a sugar alcohol that is used as a sweetener and humectant in various food and cosmetic products. It is also known for its laxative properties and is often used in combination with polyethylene glycol to enhance its effectiveness.

When polyethylene glycol sorbitol is ingested, it passes through the stomach and enters the colon, where it attracts water molecules and softens the stools. This makes it easier to pass the stools and relieves constipation.

Polyethylene glycol sorbitol is generally safe to use and does not cause any significant side effects. However, some individuals may experience mild abdominal cramps, bloating, and diarrhea.

Overall, polyethylene glycol sorbitol is a highly effective laxative that can provide relief from constipation. It is widely available over-the-counter and can be used as directed to achieve the desired results.