Sulfonamides and cotrimoxazole handwritten notes.

Introduction, classification, pharmacokinetics, resistance, uses, adverse effects, contraindications. All in detail.

Sulfonamides were the first effective antimicrobial agents. They were first effective chemotherapeutic agents. They employed systemically for prevention and cure of bacterial infections in humans. 

Cotrimoxazole  it is combination of Trimethoprim and sulfamethoxazole. They were clinically effective antimicrobial agents. They blocks the pathway of an obligate enzymatic reaction in bacteria.