SYRUP
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SYRUP
❖It’s a liquid dosage form taken to the oral route.
❖Viscous , concentrated solution of sucrose and
other sugars.
❖With ( or ) with out medicaments.
❖Flavouring agent vehicle.
❖Contain up to 85% to resist bacterial growth.
❖Intended for oral use.
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COMPONENTS
▪Sucrose ( or ) other substitute ( glycogenic
or non-glycogenic )
▪Glycogenic = sorbitol , glycerine , propyl
glycol.
▪Non – glycogenic = methyl cellulose ,
Hydroxy methyl cellulose ( suitable for
diapetic partients )
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COLOURING AGENTS
❑ Green = Mint
❑ Brown = Chocolate
❑ Red = Amaranth
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DISADVANDAGES :
• Formation of invert sugar.
• Effect the taste , stability.
• glucose + fructose
sucrose
hydrolysis heat
invert sugar form
CARAMELIZATION :
• The product become black color is sucrose is over heat is called as
caramelization.
• The process avoid maintain temperature.
sugar = 110˚C
galatose = 160˚C
glucose = 160˚C
maltose = 180˚C
saccharose = 160˚C
MEDICATED SYRUP CONTAINING A
THERAPEUTIC AGENTS
1. Demerol syrup
2. Thorazine syrup
3. Phenergan syrup
4. Lithium citrate syrup
5. Gualfenesin syrup
6. Lpecal syrup
Example for other syrup image:
CONTAINERS
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TYPES OF CONTAINERS :
1. Plastic container = colorless , brown color container mostly use
other color is available
2. Glass container = colorless , brown color form
TYPES OF CORKS :
STORAGE:
❖ It’s maintain the temperature.
❖ stable temperature.
❖ completely fill the container .
❖ no more air phase in surface of
product growth of micro organism.
❖ so completely fill the container
❖ so not completely fill the container to form microbial
organism growth.