Formulation of tablet IP2 sem7 (unit2) hand written notes pdf

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Formulation of a tablet involves several key steps, which include determining the active ingredient(s), selecting appropriate excipients, designing the tablet dosage form, and manufacturing the tablet. The following is an overview of these various steps:

1. Active Ingredient Selection: The first step in tablet formulation is to select the active ingredient(s) that will be used in the tablet. This involves evaluating the efficacy, stability, and safety profile of the active ingredient, as well as determining the optimal dose.

2. Excipient Selection: Excipients are the inactive ingredients that are used to prepare the tablet. These can include fillers, binders, lubricants, disintegrants, and other substances that help to formulate the final product. Excipient selection involves choosing ingredients that are safe, inert, and appropriate for the intended use.

3. Design of the Tablet Dosage Form: Once the active ingredient and excipients have been selected, the next step is to design the tablet dosage form. This involves assessing factors such as tablet size, shape, color, and hardness, as well as determining the appropriate release profile (e.g., immediate release, extended release, or delayed release).

4. Manufacturing the Tablet: Finally, the tablet can be manufactured using various methods such as wet granulation, dry granulation, direct compression, or molding. During the manufacturing process, the active ingredient(s) and excipients are combined into a homogeneous mixture, compressed into the desired shape, and coated (if necessary).

Overall, the formulation of a tablet requires careful consideration of a variety of factors, including the active ingredient, excipients, dosage form, and manufacturing process. By carefully designing and manufacturing each tablet, pharmaceutical companies can ensure the efficacy, stability, and safety of their products.