Therapeutic drug monitoring (TDM) is a process of measuring drug concentrations in a patient’s blood to optimize the dose of a medication to achieve the desired therapeutic effect while minimizing the risk of adverse drug reactions.
TDM is commonly used for medications with a narrow therapeutic index, such as antiepileptics, antibiotics, antiretrovirals, and immunosuppressants. The goal of TDM is to ensure that the patient receives a sufficient amount of the drug to be effective, without exceeding toxic levels that could cause harm.
TDM involves collecting blood samples from the patient at specific times after drug administration and analyzing the drug concentration in the sample using laboratory techniques such as immunoassay, chromatography, or mass spectrometry. The results of the drug concentration test are then used to adjust the dose of the medication to achieve optimal therapeutic effect.
TDM can help reduce the risk of adverse drug reactions, improve treatment outcomes, and save costs by avoiding unnecessary treatments and hospitalizations. However, TDM requires specialized equipment and expertise and can be time-consuming and expensive. Therefore, it is typically used for medications with a narrow therapeutic index or in patients with specific conditions that require close monitoring.Lacture notes downloading, Hand written notes, Pharmacy notes, MBBS notes, Study material, Dental study material, study material PDF, study material PPT, study Lacture notes, Study science notes, Drugs name, free study material PPT, PDF download Free, paramedical study notes